RNA Details
Disease Name
idiopathic pulmonary fibrosis
Tissue
lung
RNA Symbol
CXCL11
RNA ID
RNA Type
mRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
"Identification of gene-expression subsets, principal component analysis and differential gene expression; Determination of ligand-receptor interactions using single cell RNA datasets; Development of pirfenidone response signature"
Target
NA
Pathway
NA
PubMed ID
Title
Lung gene expression and single cell analyses reveal two subsets of idiopathic pulmonary fibrosis (IPF) patients associated with different pathogenic mechanisms
Year
NA
Function
"The Myeloid-enriched IPF subset (Subset 1) had increased expression of XCL1, CCL17, CCL5, CXCL9, CXCL10 and CXCL11, whereas the Ciliated epithelium-enriched IPF subset (Subset 2) had increased expression of CCL15, CXCL1, CXCL6, CCL7, CXCL17, CXCL13, CCL14 and CXCL14."